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A glimpse of work we’ve done for
forward thinking brands and clients

Diet Diurnally Regulates Small Intestinal Microbiome-Epithelial-Immune Homeostasis and Enteritis | Cell

2020

The Microbiome as a Circadian Coordinator of Metabolism | Endocrinology

2020

The microbiome-adipose tissue axis in systemic metabolism | American Journal of Physiology, Gastrointestinal and Liver Physiology

2020

TLR2 Dimerization Blockade Allows Generation of Homeostatic Intestinal Macrophages under Acute Colitis Challenge | Journal of Immunology

2020

Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner | Cell

2019, Highlights

IL-23-producing IL-10Rα-deficient gut macrophages elicit an IL-22-driven proinflammatory epithelial cell response | Science Immunology

2019

The path toward using microbial metabolites as therapies | EBioMedicine

2019

The gut microbiota regulates white adipose tissue inflammation and obesity via a family of microRNAs | Science Translational Medicine

2019

Digitalizing the Microbiome for Human Health | mSystems

2019

The Dimension of Time in Host-Microbiome Interactions | mSystems

2019

Intestinal Tolerance, with a Little Help from Our Microbial Friends Model of Colitis | Immunity

2018

Loss of MicroRNA-21 Influences the Gut Microbiota, Causing Reduced Susceptibility in a Murine Model of Colitis | Journal of Crohn’s & Colitis

2018

Hyperglycemia drives intestinal barrier dysfunction and risk for enteric infection | Science

2018, Highlights

NFIL-trating the Host Circadian Rhythm: Microbes Fine-Tune the Epithelial Clock | Cell Metabolism

2017

Ectopic colonization of oral bacteria in the intestine drives Th1 cell induction and inflammation | Science

2017

Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine | Science

2017

Circadian Coordination of Antimicrobial Responses | Cell Host & Microbe

2017

The remedy within: will the microbiome fulfill its therapeutic promise? | Journal of Molecular Medicine

2017

Post-dieting weight gain: the role of persistent microbiome changes | Future Microbiology

2017

CCR2 Regulates the Immune Response by Modulating the Interconversion and Function of Effector and Regulatory T Cells | Journal of Immunology

2017

Dysbiosis and the immune system | Nature Reviews Immunology

2017

NLRP6: A Multifaceted Innate Immune Sensor | Trends in Immunology

2017

Microbiota Diurnal Rhythmicity Programs Host Transcriptome Oscillations | Cell

2016, Highlights

Persistent microbiome alterations modulate the rate of post-dieting weight regain | Nature

2016, Highlights

The Spectrum and Regulatory Landscape of Intestinal Innate Lymphoid Cells Are Shaped by the Microbiome | Cell

2016, Highlights

Metabolites: messengers between the microbiota and the immune system | Genes & Development

2016

Microglia development follows a stepwise program to regulate brain homeostasis | Science

2016

It’s in the Milk: Feeding the Microbiome to Promote Infant Growth | Cell Metabolism

2016

Integration of Innate Immune Signaling | Trends in Immunology

2016

Microbiota-Modulated Metabolites Shape the Intestinal Microenvironment by Regulating NLRP6 Inflammasome Signaling | Cell

2015, Highlights

Metagenomic cross-talk: the regulatory interplay between immunogenomics and the microbiome | Genome Medicine

2015

Chance encounters | Nature

2015

Chronobiomics: The Biological Clock as a New Principle in Host-Microbial Interactions | Plos Pathogens

2015

Growth dynamics of gut microbiota in health and disease inferred from single metagenomic samples | Science

2015

NF-κB Regulation by NLRs: T Cells Join the Club | Immunity

2015

A day in the life of the meta-organism: diurnal rhythms of the intestinal microbiome and its host | Gut Microbes

2015

Taming the inflammasome | Nature Medicine

2015

Inflammasomes and the microbiota–partners in the preservation of mucosal homeostasis | Seminars in Immunopathology

2015

Transkingdom control of microbiota diurnal oscillations promotes metabolic homeostasis | Cell

2014, Highlights

Artificial sweeteners induce glucose intolerance by altering the gut microbiota | Nature

2014

A simple cage-autonomous method for the maintenance of the barrier status of germ-free mice during experimentation | Laboratory Animals

2014

The cross talk between microbiota and the immune system: metabolites take center stage | Current Opinion in Immunology

2014

Exploring new horizons in microbiome research | Cell Host & Microbe

2014

The interplay between the innate immune system and the microbiota | Current Opinion in Immunology

2014

Inflammasomes and metabolic disease | Annual Review of Physiology

2014

Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms | Nature Reviews Cancer

2013

Role of the intestinal microbiome in liver disease | Journal of Autoimmunity

2013

Analysis of microbiota alterations in inflammasome-deficient mice | Methods in Molecular Biology

2013

The intestinal microbiota in chronic liver disease | Advances in Immunology

2013

NLRP10 is a NOD-like receptor essential to initiate adaptive immunity by dendritic cells | Nature

2012

Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity | Nature

2012

Recent developments in the epidemiology and management of tuberculosis – new solutions to old problems? | Infection and Drug Resistance

2012

NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis | Cell

2011

Chemokines: a new dendritic cell signal for T cell activation | Frontiers in Immunology

2011

Toward Novel Vaccines Against Tuberculosis: Current Hopes and Obstacles | Yale Journal of Biology and Medicine

2010

Alternative cross-priming through CCL17-CCR4- mediated attraction of CTLs toward NKT cell–licensed DCs | Nature Immunology

2010

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